{"id":6532,"date":"2024-05-13T15:36:00","date_gmt":"2024-05-13T07:36:00","guid":{"rendered":"https:\/\/ai-stack.ai\/alphafold-3"},"modified":"2024-12-09T14:10:24","modified_gmt":"2024-12-09T06:10:24","slug":"alphafold-3","status":"publish","type":"post","link":"https:\/\/ai-stack.ai\/ja\/alphafold-3","title":{"rendered":"AlphaFold 3: AI\u751f\u7269\u79d1\u5b66\u306e\u5927\u8e8d\u9032"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">\u751f\u547d\u79d1\u5b66\u306e\u7814\u7a76\u306f\u3001\u4eba\u985e\u304c\u81ea\u8eab\u3068\u81ea\u7136\u754c\u306e\u795e\u79d8\u3092\u63a2\u6c42\u3059\u308b\u91cd\u8981\u306a\u9053\u7b4b\u3067\u3059\u3002\u3053\u306e\u904e\u7a0b\u3067\u3001\u6211\u3005\u306f\u3057\u3070\u3057\u3070\u69d8\u3005\u306a\u8ab2\u984c\u3084\u969c\u58c1\u306b\u76f4\u9762\u3057\u307e\u3059\u3002\u305d\u306e\u4e2d\u3067\u3082\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u3084DNA\u3001RNA\u306a\u3069\u306e\u751f\u4f53\u9ad8\u5206\u5b50\u306e\u4e09\u6b21\u5143\u69cb\u9020\u3084\u3001\u305d\u308c\u3089\u306e\u76f8\u4e92\u4f5c\u7528\u3092\u89e3\u660e\u3059\u308b\u3053\u3068\u306f\u3001\u751f\u7269\u5b66\u8005\u305f\u3061\u304c\u61f8\u547d\u306b\u53d6\u308a\u7d44\u3093\u3067\u304d\u305f\u96e3\u984c\u306e\u4e00\u3064\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">X\u7dda\u7d50\u6676\u89e3\u6790\u3084\u6838\u78c1\u6c17\u5171\u9cf4\u306a\u3069\u306e\u5f93\u6765\u306e\u5b9f\u9a13\u624b\u6cd5\u306f\u3001\u7cbe\u5bc6\u306a\u69cb\u9020\u60c5\u5831\u3092\u63d0\u4f9b\u3057\u307e\u3059\u304c\u3001\u591a\u304f\u306e\u6642\u9593\u3068\u30b3\u30b9\u30c8\u3092\u8981\u3057\u307e\u3059\u3002\u3053\u308c\u304c\u751f\u547d\u5206\u5b50\u306e\u7814\u7a76\u9032\u5c55\u3092\u5927\u304d\u304f\u5236\u9650\u3057\u3066\u304d\u307e\u3057\u305f\u3002\u3057\u304b\u3057\u3001\u4eba\u5de5\u77e5\u80fd\u6280\u8853\u306e\u6025\u901f\u306a\u767a\u5c55\u306b\u3088\u308a\u3001\u3053\u306e\u72b6\u6cc1\u306f\u5909\u308f\u308a\u3064\u3064\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">2020\u5e74\u3001Google DeepMind\u306fAlphaFold 2\u3092\u767a\u8868\u3057\u3001\u7b2c14\u56de\u30bf\u30f3\u30d1\u30af\u8cea\u69cb\u9020\u4e88\u6e2c\u91cd\u8981\u8a55\u4fa1(CASP14)\u30c1\u30e3\u30ec\u30f3\u30b8\u30672\u4f4d\u306b\u5927\u5dee\u3092\u3064\u3051\u3066\u512a\u52dd\u3057\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u6298\u308a\u305f\u305f\u307f\u554f\u984c\u306b\u753b\u671f\u7684\u306a\u89e3\u6c7a\u3092\u3082\u305f\u3089\u3057\u307e\u3057\u305f\u3002\u305d\u3057\u30662024\u5e745\u6708\u3001DeepMind\u306f\u518d\u3073AlphaFold\u306e\u6700\u65b0\u9032\u5316\u7248\u3067\u3042\u308bAlphaFold 3\u3092\u767a\u8868\u3057\u3001\u751f\u7269\u5b66\u5206\u91ce\u306b\u304a\u3051\u308b\u4eba\u5de5\u77e5\u80fd\u306e\u5fdc\u7528\u3092\u65b0\u305f\u306a\u9ad8\u307f\u3078\u3068\u62bc\u3057\u4e0a\u3052\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<span class=\"embed-youtube\" style=\"text-align:center; display: block;\"><iframe class=\"youtube-player\" width=\"1300\" height=\"732\" src=\"https:\/\/www.youtube.com\/embed\/9ufplEgtq8w?version=3&#038;rel=1&#038;showsearch=0&#038;showinfo=1&#038;iv_load_policy=1&#038;fs=1&#038;hl=ja&#038;autohide=2&#038;wmode=transparent\" allowfullscreen=\"true\" style=\"border:0;\" sandbox=\"allow-scripts allow-same-origin allow-popups allow-presentation allow-popups-to-escape-sandbox\"><\/iframe><\/span>\n<\/div><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>AlphaFold 3\u306e\u6838\u5fc3\u80fd\u529b<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">AlphaFold 3\u306f\u5f37\u529b\u306aAI\u30e2\u30c7\u30eb\u3067\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u69cb\u9020\u4e88\u6e2c\u3060\u3051\u3067\u306a\u304f\u3001DNA\u3001RNA\u3001\u85ac\u7269\u306a\u3069\u306e\u5c0f\u5206\u5b50\u3092\u542b\u3080\u69d8\u3005\u306a\u751f\u4f53\u5206\u5b50\u306e\u69cb\u9020\u3084\u3001\u305d\u308c\u3089\u306e\u76f8\u4e92\u4f5c\u7528\u3082\u4e88\u6e2c\u3067\u304d\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308aAlphaFold 3\u306f\u3001\u3042\u3089\u3086\u308b\u751f\u547d\u5206\u5b50\u3092\u30ab\u30d0\u30fc\u3059\u308b\u6c4e\u7528\u30e2\u30c7\u30eb\u3068\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u524d\u4e16\u4ee3\u306eAlphaFold\u3068\u6bd4\u8f03\u3057\u3066\u3001AlphaFold 3\u306f\u4e88\u6e2c\u7cbe\u5ea6\u3068\u9069\u7528\u7bc4\u56f2\u306e\u4e21\u9762\u3067\u5927\u5e45\u306a\u5411\u4e0a\u3092\u9054\u6210\u3057\u307e\u3057\u305f\u3002\u85ac\u7269\u69d8\u5c0f\u5206\u5b50\u3068\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u7d50\u5408\u69d8\u5f0f\u3092\u4e88\u6e2c\u3059\u308bPoseBusters\u30d9\u30f3\u30c1\u30de\u30fc\u30af\u30c6\u30b9\u30c8\u3067\u306f\u3001AlphaFold 3\u306f\u65e2\u5b58\u306e\u6700\u826f\u624b\u6cd5\u3088\u308a\u308250%\u9ad8\u3044\u4e88\u6e2c\u7cbe\u5ea6\u3092\u793a\u3057\u3001\u3053\u306e\u8ab2\u984c\u3067\u7269\u7406\u7684\u624b\u6cd5\u3092\u51cc\u99d5\u3057\u305f\u521d\u306eAI\u30b7\u30b9\u30c6\u30e0\u3068\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">AlphaFold 3\u306e\u52d5\u4f5c\u539f\u7406\u306f\u4f55\u3067\u3057\u3087\u3046\u304b\uff1f\u305d\u308c\u306f\u300cEvoformer\u300d\u3068\u547c\u3070\u308c\u308b\u6df1\u5c64\u5b66\u7fd2\u30a2\u30fc\u30ad\u30c6\u30af\u30c1\u30e3\u3092\u63a1\u7528\u3057\u3001\u5927\u91cf\u306e\u65e2\u77e5\u69cb\u9020\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3092\u884c\u3044\u3001\u30a2\u30df\u30ce\u9178\u914d\u5217\u3068\u30bf\u30f3\u30d1\u30af\u8cea\u69cb\u9020\u9593\u306e\u5bfe\u5fdc\u95a2\u4fc2\u3092\u5b66\u7fd2\u3057\u307e\u3059\u3002\u65b0\u3057\u3044\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u69cb\u9020\u3092\u4e88\u6e2c\u3059\u308b\u969b\u3001AlphaFold 3\u306f\u307e\u305a\u30a2\u30df\u30ce\u9178\u914d\u5217\u3092\u51e6\u7406\u3057\u3001\u305d\u306e\u5f8c\u62e1\u6563\u30e2\u30c7\u30eb\u306b\u4f3c\u305f\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u3092\u4f7f\u7528\u3057\u3066\u3001\u539f\u5b50\u306e\u96f2\u304b\u3089\u59cb\u3081\u3066\u5f90\u3005\u306b\u6700\u9069\u5316\u3068\u53ce\u675f\u3092\u884c\u3044\u3001\u6700\u7d42\u7684\u306b\u7cbe\u5bc6\u306a\u5206\u5b50\u69cb\u9020\u3092\u751f\u6210\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>AlphaFold 3\u306e\u751f\u7269\u533b\u85ac\u5206\u91ce\u3067\u306e\u5fdc\u7528<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">AlphaFold 3\u306f\u751f\u7269\u533b\u85ac\u5206\u91ce\u3067\u5e83\u7bc4\u306a\u5fdc\u7528\u306e\u53ef\u80fd\u6027\u3092\u79d8\u3081\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u4e2d\u3067\u3082\u6700\u3082\u91cd\u8981\u306a\u65b9\u5411\u6027\u306e\u4e00\u3064\u304c\u5275\u85ac\u3067\u3059\u3002\u65b0\u85ac\u306e\u958b\u767a\u306b\u306f\u81a8\u5927\u306a\u6642\u9593\u3068\u8cc7\u91d1\u304c\u5fc5\u8981\u3067\u3001\u305d\u306e\u5927\u90e8\u5206\u306f\u30ea\u30fc\u30c9\u5316\u5408\u7269\u306e\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u3068\u6700\u9069\u5316\u306b\u8cbb\u3084\u3055\u308c\u307e\u3059\u3002\u5f93\u6765\u306e\u85ac\u7269\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u6cd5\u3067\u3042\u308b\u30cf\u30a4\u30b9\u30eb\u30fc\u30d7\u30c3\u30c8\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u306f\u3001\u5927\u91cf\u306e\u5316\u5408\u7269\u30e9\u30a4\u30d6\u30e9\u30ea\u304b\u3089\u6d3b\u6027\u3092\u6301\u3064\u5206\u5b50\u3092\u63a2\u7d22\u3067\u304d\u307e\u3059\u304c\u3001\u507d\u967d\u6027\u7387\u304c\u9ad8\u304f\u3001\u7279\u7570\u6027\u306b\u6b20\u3051\u308b\u306a\u3069\u306e\u554f\u984c\u304c\u3042\u308a\u307e\u3057\u305f\u3002 AlphaFold 3\u3092\u5229\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u30b3\u30f3\u30d4\u30e5\u30fc\u30bf\u4e0a\u3067\u5c0f\u5206\u5b50\u3068\u6a19\u7684\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u7d50\u5408\u3092\u30b7\u30df\u30e5\u30ec\u30fc\u30b7\u30e7\u30f3\u3057\u3001\u305d\u306e\u89aa\u548c\u6027\u3068\u7d50\u5408\u69d8\u5f0f\u3092\u8fc5\u901f\u306b\u4e88\u6e2c\u3057\u3001\u5019\u88dc\u85ac\u7269\u306e\u7bc4\u56f2\u3092\u5927\u5e45\u306b\u7d5e\u308a\u8fbc\u3080\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u540c\u6642\u306b\u3001\u85ac\u7269\u5206\u5b50\u3068\u6a19\u7684\u3068\u306e\u7d50\u5408\u69d8\u5f0f\u3092\u6700\u9069\u5316\u3059\u308b\u3053\u3068\u3067\u3001\u85ac\u7269\u306e\u9078\u629e\u6027\u3068\u6709\u52b9\u6027\u3092\u9ad8\u3081\u3001\u526f\u4f5c\u7528\u3092\u4f4e\u6e1b\u3059\u308b\u3053\u3068\u3082\u53ef\u80fd\u3067\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u65b0\u85ac\u958b\u767a\u306e\u30d7\u30ed\u30bb\u30b9\u304c\u5927\u5e45\u306b\u52a0\u901f\u3055\u308c\u3001\u65b0\u85ac\u306e\u5e02\u5834\u6295\u5165\u307e\u3067\u306e\u6642\u9593\u304c\u77ed\u7e2e\u3055\u308c\u3001\u591a\u304f\u306e\u60a3\u8005\u306b\u6069\u6075\u3092\u3082\u305f\u3089\u3059\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>AlphaFold 3\u304c\u63a8\u9032\u3059\u308b\u57fa\u790e\u751f\u7269\u5b66\u7814\u7a76<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">AlphaFold 3\u306e\u5f71\u97ff\u306f\u751f\u7269\u533b\u85ac\u5206\u91ce\u306b\u3068\u3069\u307e\u3089\u305a\u3001\u57fa\u790e\u751f\u7269\u5b66\u7814\u7a76\u306b\u304a\u3044\u3066\u3082\u5927\u304d\u306a\u5a01\u529b\u3092\u767a\u63ee\u3057\u3066\u3044\u307e\u3059\u3002\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u69cb\u9020\u3068\u6a5f\u80fd\u306e\u7406\u89e3\u306f\u3001\u751f\u7269\u5b66\u306e\u4e2d\u6838\u7684\u306a\u8ab2\u984c\u306e\u4e00\u3064\u3067\u3059\u3002\u30bf\u30f3\u30d1\u30af\u8cea\u306f\u3001\u9175\u7d20\u89e6\u5a92\u3001\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u3001\u514d\u75ab\u5fdc\u7b54\u3001\u7d30\u80de\u9aa8\u683c\u306e\u69cb\u7bc9\u306a\u3069\u3001\u307b\u307c\u3059\u3079\u3066\u306e\u751f\u547d\u6d3b\u52d5\u306b\u95a2\u4e0e\u3057\u3066\u3044\u307e\u3059\u3002\u305d\u3057\u3066\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u6a5f\u80fd\u306f\u3001\u305d\u306e\u72ec\u7279\u306e\u4e09\u6b21\u5143\u69cb\u9020\u306b\u5927\u304d\u304f\u4f9d\u5b58\u3057\u3066\u3044\u307e\u3059\u3002\u3057\u305f\u304c\u3063\u3066\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u69cb\u9020\u306e\u89e3\u6790\u306f\u3001\u305d\u306e\u751f\u7269\u5b66\u7684\u6a5f\u80fd\u3092\u7406\u89e3\u3059\u308b\u57fa\u790e\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3057\u304b\u3057\u3001\u30d2\u30c8\u30b2\u30ce\u30e0\u30d7\u30ed\u30b8\u30a7\u30af\u30c8\u304c\u5b8c\u4e86\u3057\u3066\u304b\u308920\u5e74\u4ee5\u4e0a\u7d4c\u3063\u305f\u4eca\u3067\u3082\u3001\u4eba\u4f53\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u69cb\u9020\u306b\u95a2\u3059\u308b\u6211\u3005\u306e\u7406\u89e3\u306f\u9650\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306f\u4e3b\u306b\u3001\u5b9f\u9a13\u7684\u306b\u30bf\u30f3\u30d1\u30af\u8cea\u69cb\u9020\u3092\u6c7a\u5b9a\u3059\u308b\u3053\u3068\u304c\u975e\u5e38\u306b\u96e3\u3057\u304f\u3001\u9032\u5c55\u304c\u9045\u3044\u305f\u3081\u3067\u3059\u3002AlphaFold\u306e\u767b\u5834\u306f\u3001\u3053\u306e\u72b6\u6cc1\u3092\u6839\u672c\u7684\u306b\u5909\u3048\u308b\u53ef\u80fd\u6027\u3092\u79d8\u3081\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">2021\u5e747\u6708\u3001DeepMind\u306f\u30d2\u30c8\u306e\u5168\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u69cb\u9020\u4e88\u6e2c\u3092\u767a\u8868\u3057\u3001\u4eba\u4f53\u5185\u306e\u65e2\u77e5\u306e\u7d042\u4e07\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u30ab\u30d0\u30fc\u3057\u307e\u3057\u305f\u30022022\u5e747\u6708\u306b\u306f\u3001AlphaFold\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u3092\u3055\u3089\u306b\u62e1\u5f35\u3057\u3001200\u4e07\u4ee5\u4e0a\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u69cb\u9020\u3092\u542b\u3081\u3001\u79d1\u5b66\u754c\u3067\u65e2\u77e5\u306e\u307b\u307c\u3059\u3079\u3066\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u914d\u5217\u3092\u30ab\u30d0\u30fc\u3059\u308b\u307e\u3067\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u3053\u306e\u753b\u671f\u7684\u306a\u6210\u679c\u306f\u3001\u69cb\u9020\u751f\u7269\u5b66\u304c\u5168\u304f\u65b0\u3057\u3044\u6642\u4ee3\u306b\u5165\u3063\u305f\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>\u7d50\u8ad6<\/strong><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">AlphaFold 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